Author

B. Aryal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Cell Biology· 2 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 4 Research Focus:development & morphogenesis· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:metabolomics· 2 Organism:plant (other)· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

C. Fernandez-Hernando· 3 shared N. Rotllan· 2 shared X. Zhang· 2 shared A. Baral· 1 shared A. Canfran-Duque· 1 shared A. Dardik· 1 shared A. K. Singh· 1 shared A. Ntokou· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

C. Fernandez-Hernando

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Author profile →

7 papers

Recent·Most cited

Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease

S. P. Srivastava, H. Zhou, R. Shenoi, M. Morris, L. Goedeke, B. K. Rajendran, O. Setia, B. Aryal, K. Kanasaki, D. Koya, A. Dardik, T. Bell, C. Fernandez-Hernando, G. Shulman, J. E. Goodwin

This study identifies Angptl4 as a fibrogenic molecule in diabetic kidney disease and shows that targeting its expression in kidneys reduces fibrosis and proteinuria.

bioRxiv · Nov 8, 2023Cell Biology

A phospho-switch provided by LRR receptor-like kinase, ALK1/QSK1/KIN7, prioritizes ABCG36/PEN3/PDR8 transport toward defense

B. Aryal, J. Xia, Z. Hu, T. Tsering, J. Liu, J. Huynh, Y. Fukao, N. Gloeckner, H. Y. Huang, G. Sancho-Andres, K. Pakula, K. Gorzolka, M. Zwiewka, T. Nodzynski, K. Harter, , M. M. Geisler

This study identifies a phospho-switch mechanism involving ALK1 and ABCG36 that prioritizes defense-related transport over growth in Arabidopsis.

bioRxiv · May 11, 2022 · PreprintPlant Biology

Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

I. Kabir, X. Zhang, J. Dave, R. Chakraborty, R. Qu, R. R. Chandran, A. Ntokou, E. Gallardo-Vara, B. Aryal, N. Rotllan, R. Garcia-Milian, J. Hwa, Y. Klugar, K. A. Martin, C. Fernandez-Hernando, D. M. Greif

This study shows that aged bone marrow-derived cells increase smooth muscle cell polyclonality in atherosclerotic plaques through reduced TET2 and increased TNF signaling.

bioRxiv · Jan 18, 2022Cell Biology

In Silico Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target

R. Marahatha, S. Basnet, B. R. Bhattarai, P. Budhathoki, B. Aryal, B. Adhikari, G. Lamichhane, D. K. Poudel, N. Parajuli

This paper identifies sixteen secondary metabolites with inhibitory activity against XO and HMGR through in-silico analysis, showing potential as drug candidates for hypercholesterolemia treatment.

bioRxiv · Jul 24, 2020 · PreprintBiochemistry

Xyloglucan remodelling defines differential tissue expansion in plants

S. M. Velasquez, X. Guo, M. Gallemi, B. Aryal, P. Venhuizen, E. Barbez, K. Dünser, M. Darino, A. Pencik, O. Novak, M. Kalyna, G. Mouille, E. Benkova, R. Bhalerao, J. Mravec, J. Kleine-Vehn

The paper shows that auxin regulates xyloglucan complexity, which affects cell wall mechanics and differential growth in plant hypocotyls.

bioRxiv · Jun 21, 2020 · PreprintPlant Biology

Liver-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice

A. K. Singh, B. Chaube, A. Canfran-Duque, X. Zhang, N. L. Price, B. Aryal, J. Sun, K. M. Citrin, N. Rotllan, R. Lee, Y. Suarez, C. Fernandez-Hernando

This study shows that liver-specific ANGPTL4 suppression improves obesity-related diabetes and reduces atherosclerosis in mice by enhancing lipid metabolism and reducing inflammation.

bioRxiv · Jun 2, 2020Physiology

External mechanical cues reveal core molecular pathway behind tissue bending in plants

A. Baral, E. Morris, B. Aryal, K. Jonsson, S. Verger, T. Xu, M. J. Bennett, O. Hamant, R. P. Bhalerao

The paper shows that external mechanical cues drive hook formation in plant hypocotyls, with non-canonical auxin pathways and cellulose microfibrils playing key roles.

bioRxiv · Mar 5, 2020Plant Biology