Author

B. K. Singh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 5 Cell Biology· 2 Microbiology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 4 Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:ecology & biodiversity· 3 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 3

Frequent Co-Authors

M. Delgado-Baquerizo· 3 shared F. T. Maestre· 2 shared J. Zhou· 2 shared M. Goyal· 2 shared P. B. Reich· 2 shared P. M. Yen· 2 shared R. Dzikowski· 2 shared A. A. Renchon· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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3 shared papersEcology

M. Delgado-Baquerizo

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Author profile →

10 papers

Recent·Most cited

Complementary effects of above- and belowground biodiversity on ecosystem functions across global grasslands

C. S. C. Martins, M. Delgado-Baquerizo, R. H. Jayaramaiah, J.-T. Wang, T. Saez-Sandino, H. Liu, F. T. Maestre, P. B. Reich, B. K. Singh

The paper investigates how plant and soil microbial diversity contribute to ecosystem functions in grasslands, finding they have unique and interactive effects under different aridity conditions.

bioRxiv · Feb 10, 2023Ecology

High-throughput tagging of endogenous loci for rapid characterization of protein function

J. Kim, A. Kratz, S. Chen, J. Sheng, L. Zhang, B. K. Singh, A. Chavez

This paper introduces HITAG, a method for high-throughput tagging of endogenous loci to study protein function, and demonstrates its use in analyzing stress granule-associated proteins.

bioRxiv · Nov 16, 2022Cell Biology

Environmental thresholds in the functional mycobiome of global drylands

E. Egidi, M. Delgado-Baquerizo, M. Berdugo, E. Guirado, D. Albanese, B. K. Singh, C. COLEINE

The paper analyzes fungal community data from global drylands to identify environmental thresholds affecting community composition and functional guilds.

bioRxiv · Mar 1, 2022 · PreprintEcology

An SR protein is essential for the recovery of malaria parasites from DNA damage and exposure to artemisinin

B. K. Singh, M. Goyal, K. Simantov, Y. Kaufman, S. Eshar, R. Dzikowski

This study identifies PfSR1 as essential for DNA damage recovery and artemisinin resistance in Plasmodium falciparum by interacting with DNA repair proteins and histone marks.

bioRxiv · Jan 11, 2021 · PreprintMicrobiology

Phosphorylation of the canonical histone H2A marks foci of damaged DNA in malaria parasite

M. Goyal, A. Heinberg, V. Mitesser, S. Kandelis-Shalev, B. K. Singh, R. Dzikowski

This study shows that Plasmodium falciparum phosphorylates PfH2A in response to DNA damage, forming foci that mark damaged chromatin and enabling a direct DNA repair assay.

bioRxiv · Nov 6, 2020Microbiology

Predicting lymphatic filariasis elimination in data-limited settings: a reconstructive computational framework for combining data generation and model discovery

M. E. Smith, E. Griswold, B. K. Singh, E. Miri, A. Eigege, S. Adelamo, J. Umaru, K. Nwodu, Y. Sambo, J. Kadimbo, J. Danyobi, F. O. Richards, E. Michael

This paper develops a computational framework that combines data generation and model discovery to predict lymphatic filariasis elimination in data-limited settings, showing it can identify local transmission models and forecast intervention impacts.

PLOS Computational Biology · Jul 21, 2020Peer-reviewedEcology

Development of an in vitro senescent hepatic cell model for metabolic studies in aging

B. K. Singh, M. Tripathi, R. Sandireddy, K. Tikno, J. Zhou, P. M. Yen

This study develops an in vitro model of senescent hepatic cells to investigate metabolic changes in aging, finding altered metabolism, signaling, and toxicity in senescent AML12 cells.

bioRxiv · Mar 31, 2020 · PreprintCell Biology

Redefining Interleukin 11 as a regeneration-limiting hepatotoxin

A. A. Widjaja, J. R. Dong, E. Adami, S. Viswanathan, B. NG, B. K. Singh, W.-W. Lim, J. Zhou, L. S. Pakkiri, S. G. Shekeran, J. Tan, S. Y. Lim, M. Wang, R. Holgate, A. Hearn, , S. A. Cook

This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.

bioRxiv · Nov 4, 2019Physiology

The fate of carbon in a mature forest under carbon dioxide enrichment

M. Jiang, B. E. Medlyn, J. E. Drake, R. A. Duursma, I. C. Anderson, C. V. M. Barton, M. M. Boer, Y. Carrillo, L. Castaneda-Gomez, L. Collins, K. Y. Crous, M. G. De Kauwe, K. M. Emmerson, S. L. Facey, A. N. Gherlenda, , A. Wujeska-Klause

This study tracks carbon fate in a mature forest under CO2 enrichment, finding that increased carbon uptake does not lead to greater sequestration, as most extra carbon is released via respiration.

bioRxiv · Jul 11, 2019Ecology

Ecological niche differentiation in soil cyanobacterial communities across the globe

C. Cano-Diaz, F. T. Maestre, D. J. Eldridge, B. K. Singh, R. D. Bardgett, N. Fierer, M. Delgado-Baquerizo

This study identifies three major soil cyanobacterial clusters with distinct environmental preferences across global ecosystems and constructs the first global atlas of soil cyanobacteria.

bioRxiv · Jan 26, 2019 · PreprintEcology