Author

S. Y. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Widjaja· 1 shared A. Hearn· 1 shared A. Hewitt· 1 shared A. Pebay· 1 shared B. K. Singh· 1 shared B. NG· 1 shared C. L. Drum· 1 shared D. A. Mackey· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. A. Widjaja

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Author profile →

2 papers

Recent·Most cited

Redefining Interleukin 11 as a regeneration-limiting hepatotoxin

A. A. Widjaja, J. R. Dong, E. Adami, S. Viswanathan, B. NG, B. K. Singh, W.-W. Lim, J. Zhou, L. S. Pakkiri, S. G. Shekeran, J. Tan, S. Y. Lim, M. Wang, R. Holgate, A. Hearn, , S. A. Cook

This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.

bioRxiv · Nov 4, 2019Physiology

Mitochondrial replacement in an iPSC model of Leber Hereditary Optic Neuropathy.

R. Wong, S. Y. Lim, S. S. Hung, S. Jackson, S. Khan, N. J. Van Bergen, E. De Smit, H. H. Liang, L. S. Kearns, L. Clarke, D. A. Mackey, A. Hewitt, I. A. Trounce, A. Pebay

The paper uses cybrid technology to replace mtDNA mutations in iPSCs derived from LHON patients, showing reduced RGC death in corrected cells.

bioRxiv · Mar 26, 2017Cell Biology