Author

B. L. Gudenas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

P. A. Northcott· 2 shared A. C. Hirbe· 1 shared A. Carlson· 1 shared A. Inoue· 1 shared B. Schwer· 1 shared C. Schmidt· 1 shared H. Jin· 1 shared J. J. Phillips· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

P. A. Northcott

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2 papers

Recent·Most cited

PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

C. Schmidt, S. Cohen, B. L. Gudenas, S. Husain, A. Carlson, S. Westelman, L. Wang, J. J. Phillips, P. A. Northcott, W. A. Weiss, B. Schwer

This study shows PRDM6 represses chromatin accessibility and alters gene expression in neuroepithelial stem cells, promoting medulloblastoma but not sufficient to drive Group 4 medulloblastoma alone.

bioRxiv · Aug 29, 2023 · PreprintCancer Biology

A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

A. Inoue, L. J. Janke, B. L. Gudenas, H. Jin, Y. Fan, J. Pare, M. R. Clay, P. A. Northcott, A. C. Hirbe, X. Cao

This paper develops a genetic mouse model of MPNST that closely mimics human tumors in genetics, histology, and transcriptome.

bioRxiv · May 3, 2021Cancer Biology