Author

S. Husain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Carlson· 1 shared A. Solanki· 1 shared B. L. Gudenas· 1 shared B. Rahman· 1 shared B. Rohrer· 1 shared B. Schwer· 1 shared C. Levine· 1 shared C. Schmidt· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Carlson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

C. Schmidt, S. Cohen, B. L. Gudenas, S. Husain, A. Carlson, S. Westelman, L. Wang, J. J. Phillips, P. A. Northcott, W. A. Weiss, B. Schwer

This study shows PRDM6 represses chromatin accessibility and alters gene expression in neuroepithelial stem cells, promoting medulloblastoma but not sufficient to drive Group 4 medulloblastoma alone.

bioRxiv · Aug 29, 2023 · PreprintCancer Biology

Motor Protein MYO1C is Critical for Photoreceptor Opsin Trafficking and Visual Function

A. Solanki, S. Walterhouse, R. Martin, E. Obert, E. Arif, B. Rahman, B. Rohrer, J. H. Lipschutz, R. D. Mukherjee, R. A. Norris, J. Sundstrom, H.-J. Knolker, S. Husain, M. R. Biswal, D. Nihalani, G. P. Lobo

This study shows that MYO1C is essential for opsin trafficking to photoreceptor outer segments and normal visual function in mice.

bioRxiv · Jun 2, 2020 · PreprintCell Biology

Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance

H. Safi, P. Gopal, S. Lingaraju, S. Ma, C. Levine, V. Dartois, M. Yee, L. Li, L. Blanc, H.-P. H. Liang, S. Husain, M. Hoque, P. Soteropoulos, T. Rustad, D. Sherman, , D. Alland

This paper identifies a novel mechanism of drug tolerance in M. tuberculosis through phase variation in the glpK gene, showing reversible frameshift mutations that contribute to treatment failure and relapse.

bioRxiv · Jul 30, 2019Microbiology