Author

B. M. Markus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 1

Frequent Co-Authors

S. Lourido· 2 shared A. M. Furuta· 1 shared B. Petrova· 1 shared C. Harding· 1 shared D. A. Fidock· 1 shared J. Okombo· 1 shared J. P. J. Saeij· 1 shared K. E. Ward· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

S. Lourido

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2 papers

Recent·Most cited

A genome-wide loss-of-function screen identifies Toxoplasma gondii genes that determine fitness in interferon gamma-activated murine macrophages

Y. Wang, L. O. Sangare, T. C. Paredes-Santos, S. Krishnamurthy, M. A. Hassan, A. M. Furuta, B. M. Markus, S. Lourido, J. P. J. Saeij

The paper uses a genome-wide CRISPR screen to identify Toxoplasma gondii genes critical for fitness in IFN-gamma-activated murine macrophages, with GRA45 shown to prevent effector aggregation and enhance parasite survival.

bioRxiv · Dec 6, 2019 · PreprintMicrobiology

Genetic screens reveal a central role for heme biosynthesis in artemisinin susceptibility

C. Harding, S. M. Sidik, B. Petrova, N. F. Gnädig, J. Okombo, K. E. Ward, B. M. Markus, D. A. Fidock, S. Lourido

The paper uses CRISPR screens to identify genetic factors affecting artemisinin susceptibility in apicomplexan parasites, revealing heme biosynthesis as a key pathway.

bioRxiv · Aug 28, 2019Microbiology