Author

L. O. Sangare

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

J. P. J. Saeij· 2 shared J. P. Saeij· 2 shared S. Krishnamurthy· 2 shared Y. Wang· 2 shared A. Dieng· 1 shared A. M. Furuta· 1 shared B. M. Markus· 1 shared B. Penn· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

J. P. J. Saeij

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Y. Wang, L. R. Hollingsworth, L. O. Sangare, T. Paredes-Santos, S. Krishnamurthy, B. Penn, H. Wu, J. P. J. Saeij

bioRxiv · Dec 13, 2023 · PreprintImmunology

Toxoplasma Membrane Inositol Phospholipid Binding Protein TgREMIND Is Essential for Secretory Organelle Function and Host Infection

R. Houngue, L. O. Sangare, T. D. Alayi, A. Dieng, T. Bitard-Feildel, C. Boulogne, C. Slomianny, C. M. Atindehou, L. A. Fanou, Y. Hathout, J. P. Saeij, I. Callebaut, S. Tomavo

bioRxiv · Mar 19, 2023 · PreprintCell Biology

Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

D. Mukhopadhyay, L. O. Sangare, L. Braun, M. A. Hakimi, J. P. Saeij

The paper identifies GRA15 as a Toxoplasma effector that promotes vacuole destruction in IFNγ-activated fibroblasts by recruiting TRAF ubiquitin ligases.

bioRxiv · Feb 24, 2020Immunology

A genome-wide loss-of-function screen identifies Toxoplasma gondii genes that determine fitness in interferon gamma-activated murine macrophages

Y. Wang, L. O. Sangare, T. C. Paredes-Santos, S. Krishnamurthy, M. A. Hassan, A. M. Furuta, B. M. Markus, S. Lourido, J. P. J. Saeij

The paper uses a genome-wide CRISPR screen to identify Toxoplasma gondii genes critical for fitness in IFN-gamma-activated murine macrophages, with GRA45 shown to prevent effector aggregation and enhance parasite survival.

bioRxiv · Dec 6, 2019 · PreprintMicrobiology