Author

B. M. Nagalo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cancer & tumor microenvironment· 4 Research Focus:drug response / drug discovery· 4 Organism:human· 4 Organism:mouse· 4 Assay:proteomics· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

C. Dumbauld· 4 shared J. C. Chamcheu· 4 shared O. Barro· 4 shared A. T. Baker· 3 shared C. C. Simoes· 3 shared M. Borad· 3 shared M. T. Barrett· 3 shared S. R. Post· 3 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersImmunology

C. Dumbauld

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Characterization of Morreton Virus (MORV) as a Novel Oncolytic Virotherapy Platform for Liver Cancers

B. M. Nagalo, Y. Zhou, E. L. Loeuillard, C. Dumbauld, O. Barro, N. Elliott, A. T. Baker, M. Arora, J. M. Bogenberger, N. Meurice, J. Petit, P. L. S. Uson Junior, F. Aslam, J. C. Chamcheu, C. C. Simoes, , M. Borad

This study characterizes Morreton virus (MORV) as a safe and effective oncolytic virotherapy for liver cancers, showing tumor regression in animal models with lower doses than VSV.

Hepatology · Jun 1, 2023Peer-reviewedImmunology

Multi-modal Efficacy of a Chimeric Vesiculovirus Expressing the Morreton Glycoprotein in Sarcoma

C. Dumbauld, O. Barro, N. M. Elliott, Y. Zhou, M. Gabere, E. Raupach, A. T. Baker, M. T. Barrett, K. Buetow, B. Jacobs, M. Seetharam, M. Borad, B. M. Nagalo

This study develops a chimeric vesiculovirus (VMG) expressing MorV glycoprotein, showing anti-tumor effects in sarcoma models with in vitro efficacy and in vivo tumor reduction.

bioRxiv · Sep 18, 2022 · PreprintImmunology

In vivo Safety and Immunoactivity of Oncolytic Jurona Virus in Hepatocellular Carcinoma: A Comprehensive Proteogenomic Analysis

Y. Zhang, M. Tesfay, K. U. Ferdous, M. Taylor, M. N. Gabere, C. C. Simoes, C. Dumbauld, O. Barro, A. Graham, C. L. Washam, D. Alkam, A. Gies, J. C. Chamcheu, S. D. Byrum, S. R. Post, , B. M. Nagalo

This study evaluates the in vivo safety and immunoactivity of Jurona virus in hepatocellular carcinoma using proteogenomic analysis, showing tumor regression and enhanced immune responses.

bioRxiv · Sep 9, 2022 · PreprintImmunology

Identification of potential inhibitors of cutaneous Melanoma and Non-Melanoma skin cancer cells through in vitro and in silico screening of a small library of Phenolic compounds

S. T. Boateng, T. Roy, M. E. Agbo, S. Banang-Mbeumi, R.-C. N. Chamcheu, M. Bramwell, L. K. Pham, K. E. Jackson, R. A. Hill, B. M. Nagalo, T. Efimova, J. Fotie, J. C. Chamcheu

This study screens a small library of phenolic compounds in vitro and in silico to identify potential inhibitors of melanoma and non-melanoma skin cancer cells, finding several compounds with significant antitumor activity and selectivity.

bioRxiv · Feb 28, 2022 · PreprintPharmacology & Toxicology

Repurposing Live Attenuated Trivalent MMR Vaccine as Cost-effective Cancer Immunotherapy

B. M. Nagalo, Y. Zhang, M. A. Taylor, C. C. Simoes, C. Dumbauld, M. N. Gabere, O. Barro, J. C. Chamcheu, S. R. Post, T. J. Kelly, M. J. Borad, M. J. Cannon, A. Basnakian

This study shows that intratumoral MMR vaccine injections inhibit tumor growth and improve survival in mouse cancer models by enhancing cytotoxic T-cell responses.

bioRxiv · Feb 25, 2022Immunology

Transcriptional Landscape of Hepatocellular Carcinoma Reveals that Patient Ethnic-Origin Influences Patterns of Expression

R. Zayas, A. Sison, B. M. Nagalo

This study identifies ethnicity-specific gene expression patterns in hepatocellular carcinoma and suggests ethnic differences in treatment efficacy.

bioRxiv · Dec 1, 2020 · PreprintCancer Biology

Synergistic Combination of Cytotoxic Chemotherapy and Cyclin Dependent Kinase 4/6 Inhibitors in Biliary Tract Cancers

M. Arora, J. M. Bogenberger, A. M. Abdelrahman, J. Yonkus, R. Alva-Ruiz, J. L. Leiting, X. Chen, P. L. Serrano Uson, C. R. Dumbauld, A. T. Baker, S. I. Gamb, J. B. Egan, Y. Zhou, B. M. Nagalo, N. Meurice, , M. J. Borad

This study shows that combining gemcitabine/cisplatin with CDK4/6 inhibitors improves efficacy and reduces toxicity in biliary tract cancers through mechanisms involving autophagy and RRM1 reduction.

bioRxiv · Oct 26, 2020Cancer Biology