A. T. Baker

Characterization of Morreton Virus (MORV) as a Novel Oncolytic Virotherapy Platform for Liver Cancers

This study characterizes Morreton virus (MORV) as a safe and effective oncolytic virotherapy for liver cancers, showing tumor regression in animal models with lower doses than VSV.

Broad sialic acid usage amongst species D human adenovirus.

This study investigates sialic acid usage in HAdV-D viruses, showing its role in infection and potential for antiviral development.

Multi-modal Efficacy of a Chimeric Vesiculovirus Expressing the Morreton Glycoprotein in Sarcoma

This study develops a chimeric vesiculovirus (VMG) expressing MorV glycoprotein, showing anti-tumor effects in sarcoma models with in vitro efficacy and in vivo tumor reduction.

Synergistic Combination of Cytotoxic Chemotherapy and Cyclin Dependent Kinase 4/6 Inhibitors in Biliary Tract Cancers

This study shows that combining gemcitabine/cisplatin with CDK4/6 inhibitors improves efficacy and reduces toxicity in biliary tract cancers through mechanisms involving autophagy and RRM1 reduction.

The fiber knob protein of human adenovirus type 49 mediates highly efficient and promiscuous infection of cancer cell lines using a novel cell entry mechanism

This paper investigates HAdV-D49's novel cell entry mechanism, showing its pseudotyped vector efficiently infects cancer cell lines lacking known adenovirus receptors.

Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor

This study identifies sialic acid as the primary receptor for HAdV-D26, showing its role in infection and providing structural evidence.

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.

The paper investigates receptor interactions of HAdV-D26/48 fiber-knob protein, finding low affinity for CAR and no evidence of interaction with CD46 or Desmoglein 2.