Author

B. M. Spiegelman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

P. A. Dumesic· 2 shared A. Asnani· 1 shared A. Kuznetsov· 1 shared A. L. Smythers· 1 shared A. Rosenzweig· 1 shared A. Shimonty· 1 shared A. Vargas-Castillo· 1 shared C. Castro· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

P. A. Dumesic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

S. A. Khetarpal, H. Li, T. Vitale, J. Rhee, L. Grauvogel, C. Castro, M. J. Mittenbühler, N. E. Houstis, A. Vargas-Castillo, A. L. Smythers, J. Liu, C. Curtin, H.-G. Sprenger, K. A. Blackmore, A. Kuznetsov, , A. Rosenzweig

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

bioRxiv · Jan 30, 2024 · PreprintPhysiology

Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner

A. Shimonty, F. Pin, M. Prideaux, G. Peng, J. Huot, H. Kim, C. j. Rosen, B. M. Spiegelman, L. F. Bonewald

This study shows that irisin deletion affects murine osteocyte function differently in males and females, with protection in females under calcium deficiency and increased bone loss in males.

bioRxiv · Nov 6, 2023Physiology

RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha

P. A. Dumesic, S. E. Wilensky, S. Bose, J. G. Van Vranken, S. P. Gygi, B. M. Spiegelman

This study identifies RBM43 as a regulator of PGC1alpha translation, linking adipose inflammation to reduced energy expenditure and mitochondrial function in obesity.

bioRxiv · Jan 6, 2023 · PreprintCell Biology