Author

B. O'Brien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Chaturvedi· 3 shared V. Chaturvedi· 3 shared A. Clark· 1 shared A. O'riordan· 1 shared B. Ostrowsky· 1 shared B. Patella· 1 shared C. Bucher· 1 shared C. J. Wray· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

S. Chaturvedi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Biocompatible hydrogel electrodeposition enables the simultaneous preparation of multi-microinterfaces for ligand bioconjugation and multiplexed electrochemical detection

V. B. Juska, N. Moukri, P. Estrela, G. D. Maxwell, S. Hendricks, E. Santillan-Urquiza, B. O'Brien, B. Patella, R. Inguanta, A. O'riordan

The paper develops a hydrogel electrodeposition method to create multi-microinterfaces for bioconjugation and electrochemical detection, demonstrating effectiveness in complex matrices like bovine serum and milk.

bioRxiv · Aug 17, 2023 · PreprintBioengineering

Radiofrequency ablation remodels the tumor microenvironment and promotes systemic immunomodulation in pancreatic cancer

E. Y. Faraoni, N. C. Thosani, B. O'Brien, L. N. Strickland, V. Y. Mota, J. K. Chaney, P. Cen, J. Rowe, J. C. Cardenas, K. L. Poulsen, C. J. Wray, J. Bailey-Lundberg

This study shows radiofrequency ablation reduces tumor growth and alters the tumor microenvironment in a mouse model of pancreatic cancer, suggesting potential for combination therapies.

bioRxiv · Jan 7, 2022 · PreprintCancer Biology

Pan-resistant Candida auris: New York Sub-cluster Susceptible to Antifungal Combinations

B. O'Brien, J. Liang, S. Chaturvedi, J. Jacobs, V. Chaturvedi

The paper shows that pan-resistant Candida auris strains from a New York outbreak are susceptible to antifungal combinations, despite having mutations in multiple drug targets.

bioRxiv · Jun 8, 2020Microbiology

In vitro Evaluation of Antifungal Drug Combinations against Multidrug-resistant Candida auris isolates from New York Outbreak

B. O'Brien, S. Chaturvedi, V. Chaturvedi

This study evaluates two-drug antifungal combinations against multidrug-resistant Candida auris isolates, finding that flucytosine combinations are most effective in vitro.

bioRxiv · Oct 31, 2019Microbiology

Laboratory Analysis of an Outbreak of Candida auris in New York from 2016 to 2018-Impact and Lessons Learned

Y. C. Zhu, B. O'Brien, L. Leach, A. Clark, M. Bates, E. Adams, B. Ostrowsky, M. Quinn, E. Dufort, K. Southwick, R. Erazo, V. B. Haley, C. Bucher, V. Chaturvedi, R. J. Limberger, , S. Chaturvedi

This study analyzes a C. auris outbreak in New York, identifying factors contributing to its spread and demonstrating the effectiveness of new detection methods.

bioRxiv · Sep 6, 2019Microbiology