Author

K. L. Poulsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. J. Wray· 2 shared E. Y. Faraoni· 2 shared N. C. Thosani· 2 shared A. Bellar· 1 shared A. J. McCullough· 1 shared A. Kadam· 1 shared A. Kim· 1 shared A. L. Brown· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

C. J. Wray

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Radiofrequency ablation remodels the tumor microenvironment and promotes systemic immunomodulation in pancreatic cancer

E. Y. Faraoni, N. C. Thosani, B. O'Brien, L. N. Strickland, V. Y. Mota, J. K. Chaney, P. Cen, J. Rowe, J. C. Cardenas, K. L. Poulsen, C. J. Wray, J. Bailey-Lundberg

This study shows radiofrequency ablation reduces tumor growth and alters the tumor microenvironment in a mouse model of pancreatic cancer, suggesting potential for combination therapies.

bioRxiv · Jan 7, 2022 · PreprintCancer Biology

Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice

R. N. Helsley, T. Miyata, A. Kadam, V. Venkateshwari, N. Sangwan, E. C. Huang, R. Banerjee, A. L. Brown, K. K. Fung, W. Massey, C. Neumann, O. Danny, L. J. Osborn, R. C. Schugar, M. R. McMullen, , J. M. Brown

This study shows elevated trimethylamine (TMA) in alcohol-associated hepatitis patients and demonstrates that inhibiting gut microbial TMA production protects mice from ethanol-induced liver injury.

bioRxiv · Dec 31, 2021Biochemistry

Pancreatic cancer ductal cell of origin drives CD73-dependent generation of immunosuppressive adenosine

K. Singh, E. Y. Faraoni, Y. Dai, V. Chandra, E. Vucic, T. Mills, M. Pruski, T. Clark, G. Van Buren, N. C. Thosani, J. S. Bynon, C. J. Wray, D. Bar-Sagi, K. L. Poulsen, L. A. Vornik, , J. Bailey Lundberg

This study identifies CD73 as a key driver of immunosuppression in pancreatic ductal adenocarcinoma, showing its role in adenosine generation and tumor progression.

bioRxiv · Nov 29, 2021 · PreprintCancer Biology