B. P. Jena

Reprogramming the cells secretory machinery: A cystic fibrosis rescue

This study investigates the role of CFTR in porosome-mediated mucus secretion and shows that reconstituting functional porosomes from wild-type CFTR cells significantly improves mucus secretion in ΔF508 CFTR mutant cells.

Possible Mechanism of Porosome-Mediated Exosome Release

The paper investigates porosome-mediated exosome release by knocking out SPCA1 in Min6 cells, showing reduced glucose-stimulated insulin and exosome release.

Skeletal Muscle Remodeling in Immobilized Patients: Determined Using a Parameter Estimation Histomorphometric Approach

The paper applies machine learning to immunofluorescent images of human skeletal muscle to detect remodeling caused by immobilization.

Cystic fibrosis transmembrane conductance regulator (CFTR) inhibition results in mucus accumulation in human airway epithelia Calu-3 cells: Experimental and Machine Learning Studies

This study uses electron microscopy and machine learning to show that CFTR inhibition reduces secretory vesicle swelling and mucin release in Calu-3 cells, leading to mucus accumulation.

Deep Learning Strategies for Differential Expansion Microscopy

This paper describes machine learning strategies to extract morphological and biochemical information from differential expansion microscopy images.

vH+-ATPase-induced intracellular acidification is critical to glucose-stimulated insulin secretion

This study shows that vH+-ATPase-induced intracellular acidification is essential for glucose-stimulated insulin secretion in MIN6 cells.

Differential expansion microscopy

This paper introduces differential expansion microscopy (DiExM) to measure anisotropic expansion in biological specimens, revealing subcellular structural distortions during expansion.