L. Larsson

Phenotypic heterogeneity drives phage-bacteria coevolution in the intestinal tract

This study shows that phenotypic heterogeneity in bacteria affects phage-bacteria coevolution, leading to phage extinction due to genetic resistance evolution in the intestinal tract.

Vaccine-enhanced competition permits rational bacterial strain replacement in the gut

The paper demonstrates that oral vaccination combined with engineered competitor strains can exclude pathogens and replace bacterial strains in the mouse gut.

Electrical Stimulated GLUT4 Signaling Attenuates Critical Illness-Associated Muscle Wasting

This study shows chronic supramaximal electrical stimulation reduces critical illness-associated muscle wasting in rats by maintaining GLUT4 translocation and reducing protein degradation through AMPK-TBC1D4 and AMPK-FoxO3 pathways.

Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships

This study uses spatial transcriptomics to analyze HER2-positive breast tumors, revealing novel intercellular relationships and developing a model for tertiary lymphoid structures across tissues.

Skeletal Muscle Remodeling in Immobilized Patients: Determined Using a Parameter Estimation Histomorphometric Approach

The paper applies machine learning to immunofluorescent images of human skeletal muscle to detect remodeling caused by immobilization.

Hand-reared wolves show attachment comparable to dogs and use human caregiver as a social buffer in the Strange Situation Test

This study compares attachment behaviors between hand-reared wolves and dogs using the Strange Situation Test, finding wolves show comparable attachment and use humans as a social buffer.