Author

P. P. Borbat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Organism:E. coli· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:electronic health records· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. H. Freed· 3 shared E. R. Georgieva· 2 shared A. BriegeliD· 1 shared A. Muok· 1 shared A. R. Thiam· 1 shared B. E. Moeller· 1 shared B. R. Crane· 1 shared C. Court· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiochemistry

J. H. Freed

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Author profile →

5 papers

Recent·Most cited

A comparative study of influenza A M2 protein conformations in DOPC/DOPS liposomes and in native E. coli membranes

G. Sanders, P. P. Borbat, E. R. Georgieva

This study compares the conformation of influenza A M2 protein in model and native E. coli membranes using ESR and DEER spectroscopy, finding similar tetrameric structures.

bioRxiv · Jan 8, 2024 · PreprintBiophysics

The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins

M. C. Adams, C. J. Schiltz, J. Sun, C. J. Hosford, V. M. Johnson, H. Pan, P. P. Borbat, J. H. Freed, L. C. Thomason, C. Court, D. L. Court, J. S. Chappie

This paper presents the crystal structure of bacteriophage lambda RexA, revealing its DNA binding properties and evolutionary insights into phage exclusion mechanisms.

bioRxiv · Aug 31, 2023Microbiology

HIV-1 Vpu protein forms stable oligomers in aqueous solution via its transmembrane domain self-association

S. Majeed, L. Dang, M. M. Islam, O. Ishola, P. P. Borbat, S. J. Ludtke, E. R. Georgieva

The paper shows HIV-1 Vpu forms stable aqueous oligomers via its transmembrane domain self-association, identified through cryoEM, EPR, and size exclusion chromatography.

bioRxiv · May 8, 2023Biophysics

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Y.-M. Choi, D. Ajjaji, K. D. Fleming, P. P. Borbat, M. L. Jenkins, B. E. Moeller, S. Fernando, S. R. Bhatia, J. H. Freed, J. E. Burke, A. R. Thiam, M. V. Airola

The paper investigates how lipid composition, specifically phosphatidic acid and diacylglycerol, affects PLIN3 recruitment to membranes and LDs, revealing structural changes in the PAT domain.

bioRxiv · Nov 17, 2022Biochemistry

Engineered chemotaxis core signaling units indicate a constrained kinase-off state

A. Muok, T. Khiang Chua, M. Srivastava, W. Yang, Z. Maschmann, P. P. Borbat, J. Chong, S. Zhang, J. H. Freed, A. Briegel, B. R. Crane

The paper investigates how engineered chemoreceptor complexes stabilize a kinase-off state by sequestering kinase and substrate domains, using multiple biophysical techniques.

Science Signaling · Nov 10, 2020Peer-reviewedBiochemistry