Author

B. Romartinez-Alonso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. C. Leney· 1 shared A. Hasan· 1 shared A. J. Hudson· 1 shared B. Thurairajah· 1 shared C. Bueno-Alejo· 1 shared C. Dominguez· 1 shared D. F. Kay· 1 shared F. W. Muskett· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. C. Leney

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Author profile →

2 papers

Recent·Most cited

Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation

J. A. Ward, B. Romartinez-Alonso, D. F. Kay, J. Bellamy-Carter, B. Thurairajah, J. Basran, H. Kwon, A. C. Leney, S. Macip, P. Roversi, F. W. Muskett, R. G. Doveston

This paper characterises the phosphorylation-dependent interaction between 14-3-3σ and MDM2 and shows that small molecule stabilisation of this PPI is feasible using fusicoccin A.

bioRxiv · Sep 26, 2023Biochemistry

Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

M. Tariq, T. Ikeya, N. Togashi, L. Fairall, S. Kamei, S. Mayooramurugan, L. R. Abbott, A. Hasan, C. Bueno-Alejo, S. Sukegawa, B. Romartinez-Alonso, M. A. Muro Campillo, A. J. Hudson, Y. Ito, J. W. Schwabe, , K. Tanaka

This study investigates the structural interaction between oncogenic KRas4BG12V and Rgl2RA, revealing a unique tetrameric complex formation that explains its hyperactivation of the RalA/B pathway.

bioRxiv · Oct 10, 2022Biochemistry