B. S. Sixt

A multi-strategy antimicrobial discovery approach reveals new ways to combat Chlamydia

This paper identifies over sixty new antichlamydial compounds through a multi-strategy approach, showing potent, selective, and non-toxic activity against Chlamydia.

The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

The study shows that Cdu1's acetylase activity protects Chlamydia effectors from degradation, enabling bacterial exit from host cells.

The Chlamydia protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35