B. O. Schroeder

Antibiotics damage the colonic mucus barrier in a microbiota-independent manner

This study shows antibiotics damage the colonic mucus barrier independently of microbiota, leading to bacterial penetration and IBD exacerbation.

A history of repeated antibiotic usage leads to microbiota-dependent mucus defects

This study shows that repeated antibiotic use in humans leads to microbiota changes that impair intestinal mucus function in mice.

The gut commensal Blautia maintains colonic mucus function under low fiber consumption through short-chain fatty acid-mediated activation of Ffar2

This study shows that the gut bacterium Blautia helps maintain colonic mucus function under low fiber diets by producing short-chain fatty acids that activate Ffar2.

A multi-strategy antimicrobial discovery approach reveals new ways to combat Chlamydia

This paper identifies over sixty new antichlamydial compounds through a multi-strategy approach, showing potent, selective, and non-toxic activity against Chlamydia.