Repurposing Tofacitinib As An Anti-Myeloma Therapeutic To Reverse Growth-Promoting Effects Of The Bone Marrow Microenvironment
C. Lam, M. Murnane, H. Liu, G. A. Smith, S. Wong, J. Taunton, J. O. Liu, C. S. Mitsiades, B. C. Hann, B. T. Aftab, A. P. Wiita
This paper validates tofacitinib as an effective anti-myeloma therapy by reversing bone marrow microenvironment-driven growth signals in vitro and in vivo.
bioRxiv · May 28, 2017Cancer Biology