Author

J. O. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. P. Wiita· 1 shared B. C. Hann· 1 shared B. T. Aftab· 1 shared C. Lam· 1 shared C. S. Mitsiades· 1 shared C. Zhang· 1 shared D. Z. Chen· 1 shared G. A. Smith· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. P. Wiita

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain

J. Chu, Z. Qiu, J. Yang, Y. Zhou, J. Chen, K. Chen, C. Zhang, H. Cheng, N. Koylass, J. O. Liu, Y. Guan

This study identifies VRAC as an ATP-releasing channel in microglia contributing to neuropathic pain and shows dicumarol inhibits it, reducing pain behaviors in mice.

bioRxiv · Jan 8, 2023Physiology

Daily administration of low-dose daunorubicin or doxorubicin inhibits hypoxia-inducible factor 1 and tumor vascularization

Y. Yang, D. Z. Chen, S. Rey, J. O. Liu, G. L. Semenza

The paper identifies anthracyclines as HIF-1 inhibitors that reduce tumor vascularization by blocking HIF-1 target genes and angiogenesis.

bioRxiv · Jun 15, 2022 · PreprintCancer Biology

Repurposing Tofacitinib As An Anti-Myeloma Therapeutic To Reverse Growth-Promoting Effects Of The Bone Marrow Microenvironment

C. Lam, M. Murnane, H. Liu, G. A. Smith, S. Wong, J. Taunton, J. O. Liu, C. S. Mitsiades, B. C. Hann, B. T. Aftab, A. P. Wiita

This paper validates tofacitinib as an effective anti-myeloma therapy by reversing bone marrow microenvironment-driven growth signals in vitro and in vivo.

bioRxiv · May 28, 2017Cancer Biology