Author

B. W. Purse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 1

Frequent Co-Authors

A. E. Clark· 2 shared J. A. Bernatchez· 2 shared J. L. Siqueira-Neto· 2 shared L. A. Luna· 2 shared M. Coste· 2 shared S. Beck· 2 shared Z. Zhu· 2 shared C. D. Sohl· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMicrobiology

A. E. Clark

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2 papers

Recent·Most cited

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

J. A. Bernatchez, M. Coste, S. Beck, G. A. Wells, L. A. Luna, A. E. Clark, Z. Zhu, C. D. Sohl, B. W. Purse, J. L. Siqueira-Neto

This study evaluates the antiviral activity of nucleoside ProTides against Zika virus in human neural stem cells, identifying effective compounds and elucidating their mechanism of action.

bioRxiv · Jan 29, 2019Microbiology

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

J. A. Bernatchez, Z. Yang, M. Coste, J. Li, S. Beck, Y. Liu, A. E. Clark, Z. Zhu, L. A. Luna, C. Sohl, B. W. Purse, R. Li, J. L. Siqueira-Neto

The paper develops and validates a high-content imaging assay to assess antiviral activity of small-molecule inhibitors against Zika virus by detecting cytopathic effects.

bioRxiv · Apr 17, 2018Microbiology