Author

G. A. Wells

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. du Plessis· 1 shared A. E. Clark· 1 shared A. J. Steyn· 1 shared B. W. Purse· 1 shared C. Chattopadhyay· 1 shared C. D. Sohl· 1 shared E. A. Grimm· 1 shared F. Khan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. du Plessis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting IRS-1/2 in uveal melanoma inhibits in vitro cell growth, survival and migration, and in vivo tumor growth.

C. Chattopadhyay, R. Bhattacharya, J. Roszik, F. Khan, G. A. Wells, H. Villanueva, Y. Qin, R. Bhattacharya, S. Patel, E. A. Grimm

This study shows that NT157, an IRS-1/2 inhibitor, reduces uveal melanoma cell growth, survival, migration, and tumor growth in vivo.

bioRxiv · Oct 26, 2022 · PreprintCell Biology

3D microarchitecture of the human tuberculous granuloma

G. A. Wells, J. N. Glasgow, K. Nargan, K. Lumamba, R. Madansein, K. Maharaj, R. L. Hunter, T. Naidoo, P. Ramdial, L. Coetzer, S. le Roux, A. du Plessis, A. J. Steyn

This study uses 3D X-ray imaging to reveal complex, branched structures of human tuberculous granulomas, challenging the traditional view of spherical granulomas and suggesting implications for TB treatment strategies.

bioRxiv · Jun 14, 2020 · PreprintMicrobiology

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

J. A. Bernatchez, M. Coste, S. Beck, G. A. Wells, L. A. Luna, A. E. Clark, Z. Zhu, C. D. Sohl, B. W. Purse, J. L. Siqueira-Neto

This study evaluates the antiviral activity of nucleoside ProTides against Zika virus in human neural stem cells, identifying effective compounds and elucidating their mechanism of action.

bioRxiv · Jan 29, 2019Microbiology