Author

B.-C. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:fungi (other)· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

A. Accardi· 1 shared A. AlJanahi· 1 shared A. Di Lorenzo· 1 shared A. Gin· 1 shared A. Raczkowski· 1 shared C. Dunbar· 1 shared C. M. Nimigean· 1 shared C. Wu· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Accardi

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2 papers

Recent·Most cited

Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

B.-C. Lee, A. Gin, C. Wu, K. Singh, M. Grice, R. Mortlock, D. Abraham, X. Fan, Y. Zhou, A. AlJanahi, U. Choi, S. S. de Ravin, T. Shin, S. Hong, C. Dunbar

This study compares CRISPR/HDR and lentiviral transduction effects on HSPC engraftment and clonal dynamics in rhesus macaques, finding HDR-edited cells decline rapidly while lentiviral cells persist longer.

bioRxiv · Dec 13, 2023Cell Biology

Cryo-EM structures reveal bilayer remodeling during Ca2+ activation of a TMEM16 scramblase

M. E. Falzone, J. Rheinberger, B.-C. Lee, T. Peyear, L. Sasset, A. Raczkowski, E. Eng, A. Di Lorenzo, O. S. Andersen, C. M. Nimigean, A. Accardi

The paper presents cryo-EM structures of a fungal TMEM16 scramblase showing Ca2+-induced conformational changes and membrane reorganization.

bioRxiv · Nov 5, 2018Biochemistry