Author

A. Di Lorenzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

L. Rubinelli· 3 shared L. Sasset· 2 shared A. Accardi· 1 shared A. G. Wibmer· 1 shared A. Magrini· 1 shared A. Marino· 1 shared A. Mark· 1 shared A. Miani· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersCancer Biology

L. Rubinelli

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PET imaging of fibroblast activation protein alpha (FAP) detects incipient cardiotoxicity due to anthracycline chemotherapy

C.-H. Lee, O. Manzo, L. Rubinelli, S. E. Carrasco, S. Cho, T. M. Jeitner, J. W. Babich, A. Di Lorenzo, J. Kelly

This study shows that PET imaging with [68Ga]Ga-FAPI-04 detects early cardiotoxicity from anthracycline chemotherapy before echocardiography, by targeting fibroblast activation protein alpha (FAP).

bioRxiv · Sep 3, 2023 · PreprintCancer Biology

S1P controls endothelial sphingolipid homeostasis via ORMDL

L. Sasset, K. H. Chowdhury, O. L. Manzo, L. Rubinelli, C. Konrad, J. A. Maschek, G. Manfredi, W. L. Holland, A. Di Lorenzo

This study identifies S1P as the sphingolipid sensed by endothelial cells via S1PRs, revealing the S1PR/ORMDLs axis as a regulatory unit controlling sphingolipid homeostasis.

bioRxiv · Oct 22, 2021 · PreprintCell Biology

Lactoferrin as potential supplementary nutraceutical agent in COVID-19 patients: in vitro and in vivo preliminary evidences

E. Campione, C. Lanna, T. Cosio, L. Rosa, M. P. Conte, F. Iacovelli, A. Romeo, M. Falconi, C. Del Vecchio, E. Franchin, M. S. Lia, M. Minieri, C. Chiaramonte, M. Ciotti, M. Nuccetelli, , L. Bianchi

This paper investigates lactoferrin's antiviral activity against SARS-CoV-2 through in vitro and in vivo studies, showing it reduces viral RNA conversion time and inflammation markers in COVID-19 patients.

bioRxiv · Aug 11, 2020 · PreprintMicrobiology

Brown Adipose Tissue is Associated with Improved Cardiometabolic Health and Regulates Blood Pressure

T. Becher, S. Palanisamy, D. J. Kramer, S. J. Marx, A. G. Wibmer, I. Del Gaudio, S. D. Butler, C. S. Jiang, R. Vaughan, H. Schoder, A. Di Lorenzo, A. Mark, P. Cohen

This study links brown adipose tissue (BAT) to improved cardiometabolic health and blood pressure regulation in humans.

bioRxiv · Feb 8, 2020 · PreprintPhysiology

Pressure overload leads to coronary plaque formation, progression and myocardial events in ApoE-/- mice

A. Marino, Y. Zhang, L. Rubinelli, J. E. Ip, A. Di Lorenzo

This study shows that pressure overload in ApoE-/- mice leads to coronary plaque formation, progression, and myocardial events, mimicking human coronary artery disease.

bioRxiv · Feb 26, 2019Pathology

Cryo-EM structures reveal bilayer remodeling during Ca2+ activation of a TMEM16 scramblase

M. E. Falzone, J. Rheinberger, B.-C. Lee, T. Peyear, L. Sasset, A. Raczkowski, E. Eng, A. Di Lorenzo, O. S. Andersen, C. M. Nimigean, A. Accardi

The paper presents cryo-EM structures of a fungal TMEM16 scramblase showing Ca2+-induced conformational changes and membrane reorganization.

bioRxiv · Nov 5, 2018Biochemistry