TSPAN3 defines a distinct intracellular trafficking route to secretory multivesicular bodies
Jelle van den Bor, Misko L Bobeldijk, Christopher Arpad Zala, Cristina Trueba Sanchez, Clara Lalo, Barbara Adem, Jochanan A Maaijen, Emma MA Bundock, Nikki A Weijers, Zahra E. Soltani, Cecilia de Heus, Pascal Wtc Jansen, Wenyi Zheng, Samir EL Andaloussi, Nalan Liv, , Frederik J. Verweij
This study identifies TSPAN3 as a marker of a distinct secretory multivesicular body population with unique trafficking and EV composition compared to CD63-positive compartments.
bioRxiv · Aug 26, 2026 · PreprintCell Biology