Author
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Catarina Pelicano, Igor V. Chernukhin, Marleen Woelke…·Shalini V. Rao
This paper shows that IL-1-activated cancer-associated fibroblasts (iCAFs) promote STAT1-driven transcriptional reprogramming in pancreatic tumour cells, leading to chemoresistance and identifying STAT1 as a therapeutic target.
Elizabeth Alexandra Cooper, David A Posner, Colin Y.C. Lee…·Richard J. Gilbertson
This study identifies a mechanism by which skull bone marrow-derived HSPCs and CD4+ T cells promote immunotolerance in childhood brain tumours, showing that antibody therapy targeting CSF cytokines can disrupt this process and induce tumour regression.
Mélanie A. Eckersley-Maslin, Aled Parry, Marloes Blotenburg…·Wolf Reik
This study identifies Dppa2/4 as epigenetic factors that establish bivalency at developmental promoters, enabling lineage commitment by maintaining poised RNA polymerase and preventing DNA methylation.