Author

Barbara McKnight

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 4 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 5 Assay:GWAS summary statistics· 5 Organism:human· 5 Approach:statistical model· 5 Approach:benchmark study· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Bruce M. PsatyiD· 3 shared Christopher J. O’DonnelliD· 3 shared Jennifer A. BrodyiD· 3 shared Jerome I. RotteriD· 3 shared Kent D. TayloriD· 3 shared Susan R. HeckbertiD· 3 shared André Gerardus UitterlindeniD· 2 shared Andrew D. JohnsoniD· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersGenetics

Bruce M. PsatyORCID

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Author profile →

5 papers

Recent·Most cited

Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors

Florian Thibord, Derek M. Klarin, Jennifer A. Brody, Ming‐Huei Chen, Michael G. Levin, Daniel I. Chasman, Ellen L. Goode, Kristian Hveem, Maris Teder‐Laving, Ángel Martínez-Pérez, Dylan Aïssi, Delphine Daian-Bacq, Kaoru Ito, Pradeep Natarajan, Pamela L. Lutsey, , Nicholas L. Smith

This study identifies 135 genomic loci associated with venous thromboembolism risk through cross-ancestry GWAS and provides insights into biological pathways and potential therapeutic targets.

Circulation · Oct 17, 2022Peer-reviewedGenetic & Genomic Medicine

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

Brenton R. Swenson, Tin Louie, Henry J. Lin, Raúl Méndez-Giráldez, Jennifer Elizabeth Below, Cathy C. Laurie, Kathleen F. Kerr, Heather M. Highland, Timothy A. Thornton, Kelli K. Ryckman, Charles L Kooperberg, Elsayed Z. Soliman, Amanda A. Seyerle, Xiuqing Guo, Kent D. Taylor, , Nona Sotoodehnia

This study conducts a GWAS on QRS duration in Hispanic/Latino populations, identifying two new loci and confirming most previously known SNPs.

PLoS ONE · Jun 28, 2019Peer-reviewedGenetics

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

Cavin K Ward-Caviness, Paul S. de Vries, Kerri L. Wiggins, Jennifer E. Huffman, Lisa R. Yanek, Lawrence F. Bielak, Franco Giulianini, Xiuqing Guo, Marcus Edi Kleber, Tim Kacprowski, Astrid Petersman, George Davey Smith, Fernando Pires Hartwig, Jack Bowden, Gibran Hemani, , Alanna C. Morrison

This paper evaluates the causal effect of fibrinogen on coronary heart disease using Mendelian randomization, finding a small effect with multi-variant methods but not with single variant approaches.

PLoS ONE · May 10, 2019Peer-reviewedGenetics

The role of glycaemic, lipid, blood pressure and obesity risk factors as mediators of the effect of height on Coronary Artery Disease and Type 2 Diabetes Mellitus: A Mendelian Randomisation Study.

Eirini Marouli, Del Greco M. Fabiola, Christina M. Astley, Jian Yang, Shafqat Ahmad, Sonja I. Berndt, Mark J. Caulfield, Evangelos Evangelou, Barbara McKnight, Carolina Medina‐Gómez, Jana V. van Vliet‐Ostaptchouk, Helen R. Warren, Zhihong Zhu

This paper uses Mendelian Randomisation to show that height reduces coronary artery disease risk independently of BMI, lipid, and blood pressure, but has no direct effect on type 2 diabetes risk after adjusting for BMI.

bioRxiv · Nov 12, 2018 · PreprintGenetics

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

Foram N. Ashar, Rebecca N. Mitchell, Christine M. Albert, Christopher Newton‐Cheh, Jennifer A. Brody, Martina Müller‐Nurasyid, Anna Moes, Thomas Meitinger, Angel C. Y. Mak, Heikki V. Huikuri, Juhani M. Junttila, Philippe Goyette, Sara L. Pulit, Raha Pazoki, Michael W.T. Tanck, , Nona Sotoodehnia

This study evaluates the genetic architecture of sudden cardiac arrest through GWAS and Mendelian randomization, finding genetic correlations with CAD, height, BMI, and electrical instability traits.

European Heart Journal · Jul 20, 2018Peer-reviewedGenetics