Author

Ben E. Machado

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:zebrafish· 2 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne BrunetiD· 2 shared Daniel F. JarosziD· 2 shared Eitan MosesiD· 2 shared Inbal Ziv· 2 shared Itamar HareliD· 2 shared Param Priya SinghiD· 2 shared Uri GoshtchevskyiD· 2 shared Yiwen R. Chen· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Anne BrunetORCID

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2 papers

Recent·Most cited

Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate

Yiwen R. Chen, Itamar Harel, Param Priya Singh, Inbal Ziv, Eitan Moses, Uri Goshtchevsky, Ben E. Machado, Anne Brunet, Daniel F. Jarosz

This study profiles protein aggregation in seven tissues of aging killifish, revealing tissue-specific patterns linked to protein biophysics and quality control.

Developmental Cell · May 28, 2024Peer-reviewedSystems Biology

Identification of protein aggregates in the aging vertebrate brain with prion-like andphase separation properties

Itamar Harel, Yiwen R. Chen, Inbal Ziv, Param Priya Singh, Daniel Heinzer, Paloma Navarro Negredo, Uri Goshtchevsky, Wei Wang, Gwendoline Astre, Eitan Moses, Andrew S. McKay, Ben E. Machado, Katja Hebestreit, Sifei Yin, Alejandro Sánchez Alvarado, , Anne Brunet

The paper identifies prion-like and phase-separated protein aggregates in aging vertebrate brains using quantitative proteomics in killifish and validates their propagation and functional properties.

Cell Reports · May 28, 2024Peer-reviewedNeuroscience