Param Priya Singh

Killiverse provides an interactive web platform for exploring killifish multi-omics data, enabling cross-study and cross-species analysis through standardized datasets and ortholog mapping.

This study identifies brain macrophages in the African turquoise killifish that engulf brain extracellular material, showing age-related decline in engulfment capacity.

The paper creates a multi-tissue transcriptomic aging atlas in killifish, identifies age-altered pathways, and develops tissue-specific transcriptomic clocks with sex-specific biomarkers for aging prediction.

This study profiles protein aggregation in seven tissues of aging killifish, revealing tissue-specific patterns linked to protein biophysics and quality control.

The paper identifies prion-like and phase-separated protein aggregates in aging vertebrate brains using quantitative proteomics in killifish and validates their propagation and functional properties.

This study identifies regulatory innovations in ancient gene programs that drive diapause in the African turquoise killifish, linking chromatin changes to lipid metabolism and survival.

The paper characterizes gonadal transcriptome changes across lifespan in African turquoise killifish, finding sex-specific declines in piRNA pathways and TE activity in ovaries with aging.

OHNOLOGS v2 identifies and refines ohnologs from 2R- and 3R-WGD in 27 vertebrate genomes, revealing retention patterns across species.

This study analyzes epigenomic and transcriptomic changes across mouse tissues with age, identifying age-related immune pathway activation and retroviral sequence upregulation.