DDHD2 interacts with STXBP1 to mediate long-term memory via the generation of myristic acid
Isaac Oluwatobi Akefe, Benjamin Matthews, Saber H. Saber, Bharat G. Venkatesh, Rachel S. Gormal, Daniel G. Blackmore, Emma Sierecki, Yann Gambin, Jesus Bertran‐Gonzalez, Alysee A. Michaels, Mingshan Xue, Benjamin F. Cravatt, Merja Joensuu, Tristan P. Wallis, Frédéric A. Meunier
This study shows that DDHD2 and STXBP1 interact to generate myristic acid, which is essential for long-term memory formation in mice.
bioRxiv · May 11, 2023 · PreprintNeuroscience