AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth
Yann Cormerais, Samuel C. Lapp, Krystle C. Kalafut, Madi Y. Cissé, Jong Shin, Benjamin Stefadu, Jean Personnaz, Sandra Schrötter, Jessica Freed, Angelica D’Amore, Emma R. Martin, Catherine Lourdes Salussolia, Mustafa Şahin, Suchithra Menon, Vanessa Byles, Brendan D. Manning
This study shows that AKT-mediated phosphorylation of TSC2 regulates tissue-specific mTORC1 signaling and organ growth in mice.
Developmental Cell · Sep 23, 2024Peer-reviewedCell Biology