Author

Suchithra Menon

Harvard UniversityORCID 0000-0002-8604-5220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexander N.R. WeberiD· 1 shared Alfred G. ZimmerliniD· 1 shared Andreas HofmanniD· 1 shared Angelica D’AmoreiD· 1 shared Artiom CernijenkoiD· 1 shared Ashley A. Burke· 1 shared Aude Sylvain· 1 shared Azeddine ElhajoujiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alexander N.R. WeberORCID

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2 papers

Recent·Most cited

A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation

Aude Sylvain, Natacha Stoehr, Fupeng Ma, Artiom Cernijenko, Martin Schröder, Maryam Khoshouei, Melanie Vogelsanger, Michel Schoenboerner, Ashley A. Burke, Pasupuleti Rao, Jonathan M. Solomon, Joshiawa Paulk, Lei Xu, Janet Dawson, Damien Begue, , Zuni I. Bassi

This paper identifies NK7-902, a CRBN molecular glue degrader of NEK7, showing partial inhibition of NLRP3 inflammasome activation in humans and full activity in mice, but only transient effects in non-human primates.

Cell chemical biology · Jul 1, 2025Peer-reviewedImmunology

AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth

Yann Cormerais, Samuel C. Lapp, Krystle C. Kalafut, Madi Y. Cissé, Jong Shin, Benjamin Stefadu, Jean Personnaz, Sandra Schrötter, Jessica Freed, Angelica D’Amore, Emma R. Martin, Catherine Lourdes Salussolia, Mustafa Şahin, Suchithra Menon, Vanessa Byles, Brendan D. Manning

This study shows that AKT-mediated phosphorylation of TSC2 regulates tissue-specific mTORC1 signaling and organ growth in mice.

Developmental Cell · Sep 23, 2024Peer-reviewedCell Biology