Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques
Nitesh Mishra, Bo Liang, Ryan S. Roark, Amrit Raj Ghosh, Sean Callaghan, Wen-Hsin Lee, Xuduo Li, Anh L. Vo, Gabriel Avillion, Rohan Roy Chowdhury, Rumi Habib, Frédéric Bibollet‐Ruche, Gabriella Giese, Prabhgun Oberoi, Khaled Amereh, , Raiees Andrabi
This study shows that a germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques by priming V2-apex bnAb B cell precursors.
Immunity · Apr 1, 2026Peer-reviewedImmunology