Author

Amrit Raj Ghosh

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Beatrice H. HahniD· 3 shared Dennis R. BurtoniD· 3 shared Facundo D. BatistaiD· 3 shared George M. ShawiD· 3 shared Khaled AmerehiD· 3 shared Lawrence S. ShapiroiD· 3 shared Peter D. KwongiD· 3 shared Raiees AndrabiiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Beatrice H. HahnORCID

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3 papers

Recent·Most cited

Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques

Nitesh Mishra, Bo Liang, Ryan S. Roark, Amrit Raj Ghosh, Sean Callaghan, Wen-Hsin Lee, Xuduo Li, Anh L. Vo, Gabriel Avillion, Rohan Roy Chowdhury, Rumi Habib, Frédéric Bibollet‐Ruche, Gabriella Giese, Prabhgun Oberoi, Khaled Amereh, , Raiees Andrabi

This study shows that a germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques by priming V2-apex bnAb B cell precursors.

Immunity · Apr 1, 2026Peer-reviewedImmunology

Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model after a single bolus immunization

Amrit Raj Ghosh, Rumi Habib, Nitesh Mishra, Ryan S. Roark, Madhav Akauliya, Ali A. Albowaidey, Joel D. Allen, Khaled Amereh, Gabriel Avillion, Maria Bottermann, Bo Liang, Namit Chaudhary, Sean Callaghan, Jonathan Dye, Xuduo Li, , Facundo D. Batista

This study shows that a single immunization with a germline-targeting trimer can induce broad HIV-1 neutralizing antibodies in a rhesus macaque bnAb mouse model.

bioRxiv · Jun 12, 2025 · PreprintImmunology

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Rumi Habib, Ryan S. Roark, Hui Li, Andrew Jesse Connell, Michael P. Hogarty, Kshitij Wagh, Shuyi Wang, Lorie Marchitto, Ashwin N. Skelly, John W. Carey, Kirsten J. Sowers, Kasirajan Ayyanathan, Samantha J. Plante, Frédéric Bibollet‐Ruche, Young-Hoon Park, , George M. Shaw

The paper identifies B cell priming as the main obstacle to developing HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected macaques.

bioRxiv · May 3, 2025 · PreprintImmunology