Early clonal dominance at priming sets the trajectory for broad HIV serum neutralization
Bo Liang, Yuxin Zhu, Ryan S. Roark, Xuduo Li, Nitesh Mishra, Christian L. Martella, Anh L. Vo, Gabriella Giese, Qin Huang, Andrea Biju, Lifei Tjio, Rohan Roy Chowdhury, Prabhgun Oberoi, Khaled Amereh, Areeba A. Wani, , Raiees Andrabi
The paper shows that early clonal dominance in B-cell precursors after vaccination predicts the breadth of HIV-neutralizing antibodies in rhesus macaques.
bioRxiv · Oct 27, 2026 · PreprintImmunology