Author

Brhan Gebremedhin

New York Genome Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Aidan C. DalyiD· 2 shared Christopher A. JacksoniD· 2 shared Colin SmithiD· 2 shared Hemali P. PhatnaniiD· 2 shared Jacqueline EschbachiD· 2 shared Joana PetrescuiD· 2 shared Kristy KangiD· 2 shared Matthew LeungiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Aidan C. DalyORCID

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2 papers

Recent·Most cited

Distinct Cellular Phenotypes of Language and Executive Decline in Amyotrophic Lateral Sclerosis

Joana Petrescu, Cláudio Gouveia Roque, Christopher A. Jackson, Aidan C. Daly, Zoé Butti, Kristy Kang, Obadele Casel, Matthew Leung, Luke Reilly, Jacqueline Eschbach, Brhan Gebremedhin, Karina McDade, Jenna M. Gregory, Richard Bonneau, Colin Smith, Hemali P. Phatnani

The paper maps cognitive impairments in ALS by integrating spatial and single-nucleus transcriptomics, revealing distinct cellular and molecular patterns in language and executive dysfunction.

Cell · Aug 4, 2026Peer-reviewedGenomics

A multi-omics characterization reveals distinct molecular signatures in the human motor cortex and lumbar spinal cord in ALS

Natalie Barretto, Benjamin T. Fullerton, Aidan C. Daly, Obadele Casel, Olena Kuksenko, Kristy Kang, Joana Petrescu, Maya Xia, Jacqueline Eschbach, Matthew Leung, Shruti Khiste, Brhan Gebremedhin, Colin Smith, Christopher A. Jackson, Hemali P. Phatnani

This study uses multi-omics data to compare molecular signatures in the motor cortex and lumbar spinal cord of ALS patients, finding distinct alterations in MN and glial functions depending on symptom onset site.

bioRxiv · Jul 28, 2026 · PreprintGenomics