Author

Luke Reilly

National Institutes of HealthORCID 0000-0002-1037-6402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Caroline B. PantazisiD· 2 shared Daniel M. RamosiD· 2 shared Erika Lara· 2 shared Faraz FaghriiD· 2 shared Julia Stadler· 2 shared Lirong PengiD· 2 shared Marianita SantianaiD· 2 shared Mark R. CooksoniD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Caroline B. PantazisORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Distinct Cellular Phenotypes of Language and Executive Decline in Amyotrophic Lateral Sclerosis

Joana Petrescu, Cláudio Gouveia Roque, Christopher A. Jackson, Aidan C. Daly, Zoé Butti, Kristy Kang, Obadele Casel, Matthew Leung, Luke Reilly, Jacqueline Eschbach, Brhan Gebremedhin, Karina McDade, Jenna M. Gregory, Richard Bonneau, Colin Smith, Hemali P. Phatnani

The paper maps cognitive impairments in ALS by integrating spatial and single-nucleus transcriptomics, revealing distinct cellular and molecular patterns in language and executive dysfunction.

Cell · Aug 4, 2026Peer-reviewedGenomics

A reference induced pluripotent stem cell line for large-scale collaborative studies

Caroline B. Pantazis, Andrian Yang, Erika Lara, Justin A. McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kumar Kanaujiya, Jizhong Zou, David P. Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, , Florian T. Merkle

The paper identifies and characterizes a reference iPSC line, KOLF2.1J, for standardized use in collaborative studies across multiple differentiation protocols and assays.

Cell stem cell · Dec 1, 2022Peer-reviewedNeuroscience

A fully automated FAIMS-DIA proteomic pipeline for high-throughput characterization of iPSC-derived neurons

Luke Reilly, Lirong Peng, Erika Lara, Daniel M. Ramos, Michael S. Fernandopulle, Caroline B. Pantazis, Julia Stadler, Marianita Santiana, Anant Dadu, James Iben, Faraz Faghri, Mike A. Nalls, Steven L. Coon, Priyanka S. Narayan, Andrew Singleton, , Yue Andy Qi

The paper presents a fully automated FAIMS-DIA proteomic pipeline for iPSC-derived neurons, showing high protein identification and reproducibility, validated against single-cell RNA-Seq data.

bioRxiv · Nov 24, 2021 · PreprintNeuroscience