Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.
Tiffany Ge, Donna Garvey Brickner, Kara Zehr, D. Jake VanBelzen, Wenzhu Zhang, Christopher Caffalette, Gavin C. Moeller, Sara Ungerleider, Nikita Marcou, Alexis Jacob, Vu Q. C. Nguyen, Brian Chait, Michael P. Rout, Jason H. Brickner
The paper identifies Crm1 as an adaptor that links transcription factors to chromatin at the nuclear pore complex, facilitating enhancer docking.
Molecular Cell · Jan 1, 2024Peer-reviewedCell Biology