Tamar Schlick A

The paper uses the RAG framework to identify new viral RNA motifs from PDB structures, expanding the RNA Motif Atlas to 197 dual graph motifs.

The paper models X-chromosome inactivation at multiple scales, showing how chromatin reorganization drives Xist expression and silences Tsix through structural changes.

The paper investigates chromatin structure in immature and mature mouse retina cells, finding that short DNA linkers disrupt the two-start zigzag folding, leading to less compact chromatin in immature cells.

The paper investigates the RNA structures and interactions of the 5' and 3' regions of the SARS-CoV-2 frameshifting element, revealing their co-regulatory roles and implications for therapeutic interventions.

The paper shows that predicted SARS-CoV-2 FSE mutants abolish frameshifting and suppress structural transitions, highlighting the role of alternative conformations in ribosomal transitions.

This study investigates how Myc:Max binding affects chromatin architecture and gene regulation through simulations of chromatin fiber folding and microdomain formation.

The paper shows that chromatin fiber folding in quiescent yeast represses transcription and loop extrusion, with H4 tail modifications affecting fiber structure and function.

This study shows that cohesin loss eliminates loop domains, causing superenhancer links and gene downregulation, which are reversible upon cohesin restoration.