ImmunologybioRxivPreprint
Cancers modulate p53 truncal neoantigen display to evade T cell detection
Koji Haratani, Bruce B. Reinhold, Jonathan S. Duke‐Cohan…·Ellis L. Reinherz
This study identifies that cancers limit p53 neoantigen display on MHC molecules, evading T cell detection through immune selection and ERAP1-mediated destruction.
DOI 10.1101/2025.11.26.690562