Author

Connor J. Hennessey

Dana-Farber Cancer InstituteORCID 0000-0002-5579-1220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew J. AguirreiD· 3 shared Agnieszka KraftiD· 1 shared Akhouri Kishore RaghawaniD· 1 shared Alexander GuseviD· 1 shared Allyson Karmazyn· 1 shared Amanda GarzaiD· 1 shared Ananya D. JambhaleiD· 1 shared Andréanne Gagné· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Andrew J. AguirreORCID

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3 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedApr 27, 2026

GLIS3 Marks a Neural-like Progenitor Cell State that Drives Metastasis in Pancreatic Ductal Adenocarcinoma

Dennis H. Gong, Jimmy A. Guo, Jennifer Su…·William L. Hwang

This study identifies Glis3 as a key transcription factor driving metastasis in PDAC by promoting a neural-like progenitor cell state.

1 citation

mouseorganoid / primary culture

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 26, 2025

Cancers modulate p53 truncal neoantigen display to evade T cell detection

Koji Haratani, Bruce B. Reinhold, Jonathan S. Duke‐Cohan…·Ellis L. Reinherz

This study identifies that cancers limit p53 neoantigen display on MHC molecules, evading T cell detection through immune selection and ERAP1-mediated destruction.

DOI 10.1101/2025.11.26.690562

humanproteomics

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Cancer BiologyCell Reports MedicinePeer-reviewedJun 1, 2025

Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma

Josephine Yates, Camille A. Mathey-Andrews, Jihye Park…·Eliezer M. Van Allen

The paper analyzes multiomic data from primary and metastatic esophageal adenocarcinoma tumors to identify cell states and their spatial interactions, linking them to clinical outcomes.

11 citations

𝕏 PostBluesky