Gut-Liver physiomimetics reveal paradoxical modulation of IBD-related inflammation by short-chain fatty acids
M. Trapecar, C. Communal, J. Velazquez, C. A. Maass, Y.-J. Huang, K. Schneider, C. W. Wright, G. Eng, O. Yilmaz, D. L. Trumper, L. G. Griffith
The paper uses human physiomimetic systems to show short-chain fatty acids can both improve and worsen ulcerative colitis depending on CD4 T cell activation state.
bioRxiv · Aug 28, 2019Bioengineering