C. A. Sariol

CD4+ T Cell Depletion Before Primary Dengue and/or Secondary Zika Infection Reveals Mechanistic Correlates of Antibody Functionality in Rhesus Macaques.

This study shows that CD4+ T cell depletion before DENV infection affects antibody specificity and cross-reactivity during subsequent ZIKV infection in rhesus macaques.

Age, sex, and social environmental effects on immune cell composition in a free-ranging non-human primate.

This study examines how age, sex, and social status affect immune cell composition in rhesus macaques, revealing age-related immunosenescence and sex-dependent effects of social adversity.

The receptor binding domain of SARS-CoV-2 spike is the key target of neutralizing antibody in human polyclonal sera.

This study identifies the receptor binding domain (RBD) of SARS-CoV-2 spike as the primary target of neutralizing antibodies in human polyclonal sera.

Validation and performance of a quantitative IgG assay for the screening of SARS-CoV-2 antibodies

The paper validates a quantitative IgG ELISA assay for SARS-CoV-2 antibodies, showing high sensitivity, specificity, and predictive values.

Significant control of Zika infection in macaques depends on the elapsing time after dengue exposure

The paper shows that a longer interval between dengue and Zika infections improves Zika control in macaques, linked to pre-existing CD4+ T cell responses rather than antibodies.

Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

This study examines how the time between Zika and dengue virus infections affects immune responses, finding that prior Zika exposure enhances antibody and T cell responses to dengue without increasing viremia.