Author

L. Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bartke· 1 shared A. de Silva· 1 shared A. K. Pinto· 1 shared A. Ortiz-Rosa· 1 shared A. Purificacao· 1 shared A. Schneider· 1 shared B. Godoi· 1 shared B. Martin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Bartke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Unveiling the antiviral capabilities of targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2

A. Purificacao, S. Silva-Mendonca, L. Cruz, C. Sacramento, J. Temerozo, N. Fintelman-Rodrigues, C. Freitas, B. Godoi, M. Vaidergorn, J. Leite, L. Alvarez, M. Freitas, M. Silva, B. Martin, R. Lopez, , C. Nonato

This study identifies quinone-based compounds that inhibit HsDHODH and show anti-SARS-CoV-2 activity with low toxicity and nanomolar IC50.

bioRxiv · Oct 4, 2023Biochemistry

Genome-wide Association Studies Reveal Important Candidate Genes for the Bacillus pumilus TUAT-1-Arabidopsis thaliana Interaction

M. Soneghett Cotta, F. Plucani do Amaral, L. Cruz, R. Wassem, F. d. O. Pedrosa, T. Yokoyama, G. Stacey

This study uses GWAS to identify candidate genes in Arabidopsis thaliana associated with root architecture changes in response to Bacillus pumilus TUAT-1 inoculation.

bioRxiv · May 26, 2020 · PreprintPlant Biology

DNA damage and macrophage infiltration in the ovaries of the long-lived GH deficient Ames Dwarf and the short-lived bGH transgenic mice

T. D. Saccon, M. Rovani, D. Garcia, J. Pradiee, R. Mondadori, L. Cruz, C. Barros, Y. Fang, S. McFaden, A. Bartke, M. masternak, A. Schneider

This study compares DNA damage, macrophage infiltration, and granulosa cell numbers in GH-deficient and GH-overexpressing mice to assess GH's role in ovarian health.

bioRxiv · Jan 19, 2020 · PreprintPhysiology

Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

E. X. Perez-Guzman, P. Pantoja, C. Serrano-Collazo, M. A. Hassert, A. Ortiz-Rosa, I. V. Rodriguez, L. Giavedoni, V. Hodara, L. Parodi, L. Cruz, T. Arana, L. J. White, M. I. Martinez, D. Weiskopf, J. D. Brien, , C. A. Sariol

This study examines how the time between Zika and dengue virus infections affects immune responses, finding that prior Zika exposure enhances antibody and T cell responses to dengue without increasing viremia.

bioRxiv · Aug 26, 2019Microbiology