Author

C. Ashley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Aggarwal· 2 shared J. A. Triccas· 2 shared M. Steain· 2 shared A. Ashhurst· 1 shared A. Norman· 1 shared A. Stella· 1 shared B. Dcosta· 1 shared C. Counoupas· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

A. Aggarwal

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2 papers

Recent·Most cited

Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens

C. Counoupas, P. Pino, A. Stella, C. Ashley, H. Lukeman, N. Bhattacharyya, T. Tada, S. Anchisi, C. Metayer, J. Martinis, A. Aggarwal, B. Dcosta, J. Kint, M. Wurm, N. Landau, , J. A. Triccas

This study shows that Alhydroxiquim-II-adjuvanted trimeric spike antigens induce high-titre, cross-variant neutralising antibodies against SARS-CoV-2 in animal models.

bioRxiv · Aug 18, 2021Microbiology

Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display

A. Norman, C. Franck, M. Christie, P. Hawkins, K. Patel, A. Ashhurst, A. Aggarwal, J. K. Low, R. Siddiquee, C. Ashley, M. Steain, J. A. Triccas, S. G. Turville, J. Mackay, T. Passioura, R. J. Payne

The paper identifies cyclic peptide ligands to the SARS-CoV-2 spike protein RBD using mRNA display, finding six high-affinity molecules with nanomolar dissociation constants.

ACS Central Science · Jun 23, 2021Peer-reviewedBiochemistry