Author

N. Bhattacharyya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Evolutionary Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 6 Organism:human· 5 Assay:proteomics· 5 Research Focus:differential expression· 4 Assay:scRNA-seq· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3

Frequent Co-Authors

J. A. Boyce· 4 shared T. M. Laidlaw· 4 shared K. M. Buchheit· 3 shared N. A. Barrett· 3 shared A. Aggarwal· 2 shared A. K. Shalek· 2 shared A. Stella· 2 shared B. Chang· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersImmunology

J. A. Boyce

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps

N. A. Barrett, G. X. Huang, N. R. Hallen, M. Lee, K. Zheng, X. Wang, M. V. Mandanas, S. Djeddi, D. Fernandez, J. Hacker, T. Ryan, R. W. Bergmark, N. Bhattacharyya, S. Lee, A. Z. Maxfield, , M. Gutierrez-Arcelus

The paper identifies increased mTORC1 activity in CRSwNP epithelial cells and links it to cytokine production and inflammation in both CRSwNP and asthma.

bioRxiv · Oct 13, 2023 · PreprintImmunology

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

X. Wang, N. Hallen, M. Lee, S. Samuchiwal, Q. Ye, K. Buchheit, A. Maxfield, R. Roditi, R. Bergmark, N. Bhattacharyya, T. Ryan, D. Gakpo, S. Raychaudhuri, D. Dwyer, T. M. Laidlaw, , N. Barrett

This study identifies BCAM as a marker of airway basal stem cells and shows that T2 cytokines drive their expansion via IRS signaling in CRSwNP.

bioRxiv · Oct 13, 2022Immunology

Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes.

E. Hauzman, M. E. Pierotti, N. Bhattacharyya, J. H. Tashiro, C. A. Yovanovich, P. F. Campos, D. F. Ventura, B. Chang

This study identifies two functionally distinct SWS1 opsins in Helicops snakes, enabling UV and violet vision, and links this to improved visual acuity and chromatic discrimination.

bioRxiv · Sep 7, 2021Evolutionary Biology

Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens

C. Counoupas, P. Pino, A. Stella, C. Ashley, H. Lukeman, N. Bhattacharyya, T. Tada, S. Anchisi, C. Metayer, J. Martinis, A. Aggarwal, B. Dcosta, J. Kint, M. Wurm, N. Landau, , J. A. Triccas

This study shows that Alhydroxiquim-II-adjuvanted trimeric spike antigens induce high-titre, cross-variant neutralising antibodies against SARS-CoV-2 in animal models.

bioRxiv · Aug 18, 2021Microbiology

A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice

C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas

A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.

bioRxiv · Dec 10, 2020 · PreprintMicrobiology

IL-5Rα marks nasal polyp IgG4 and IgE-secreting cells in aspirin-exacerbated respiratory disease

K. M. Buchheit, D. F. Dwyer, J. Ordovas-Montanes, H. R. Katz, E. Lewis, N. Bhattacharyya, A. K. Shalek, N. A. Barrett, J. A. Boyce, T. M. Laidlaw

This study identifies IL-5Rα-expressing IgG4 and IgE-secreting cells in nasal polyps of AERD patients, linking them to disease severity and local antibody production.

bioRxiv · Jan 23, 2019 · PreprintImmunology

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

J. Ordovas-Montanes, D. F. Dwyer, S. K. Nyquist, K. M. Buchheit, C. Deb, M. H. Wadsworth, T. K. Hughes, S. W. Kazer, E. Yoshimoto, N. Bhattacharyya, H. R. Katz, T. M. Laidlaw, J. A. Boyce, N. A. Barrett, A. K. Shalek

This study profiles single-cell RNA-seq data from human respiratory tissues to show reduced epithelial diversity and altered basal progenitor states in type 2 immunity-driven diseases.

bioRxiv · Nov 14, 2017Immunology

Cone-like rhodopsin expressed in the all cone retina of the colubrid pine snake as a potential adaptation to diurnality

N. Bhattacharyya, B. Darren, R. K. Schott, V. Tropepe, B. Chang

The study identifies blue-shifted rhodopsin with cone opsin properties in the all-cone retina of Pituophis melanoleucus, suggesting evolutionary transmutation from rod ancestors as an adaptation for diurnal vision.

bioRxiv · Jan 18, 2017Evolutionary Biology