Author

C. C. Bailey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

M. Farzan· 3 shared B. Quinlan· 2 shared G. Crynen· 2 shared H. Peng· 2 shared L. Zhang· 2 shared T. Ou· 2 shared W. He· 2 shared Y. Guo· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBioengineering

M. Farzan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4

A. Pan, C. C. Bailey, T. Ou, J. Xu, X. Liu, B. Hu, G. Crynen, N. Skamangas, N. Bronkema, M. Tran, H. Mu, X. Zhang, Y. Yin, M. D. Alpert, W. He, M. Farzan

This study demonstrates that non-antibody protein biologics can undergo affinity maturation in vivo, leading to improved binding affinity and neutralization potency against HIV-1.

bioRxiv · Feb 3, 2024Bioengineering

In vivo affinity maturation of murine B cells reprogrammed to express human antibodies

Y. Yin, Y. Guo, Y. Jiang, B. Quinlan, H. Peng, G. Crynen, W. He, L. Zhang, T. Ou, C. C. Bailey, M. Farzan

This study demonstrates that CRISPR-edited murine B cells expressing human antibodies can undergo affinity maturation, generating potent neutralizing antibodies against HIV-1 and SARS-CoV-2.

bioRxiv · Oct 20, 2023 · PreprintBioengineering

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2

H. Mou, B. Quinlan, H. Peng, Y. Guo, S. Peng, L. Zhang, M. Davis-Gardner, M. Gardner, Z. X. Voo, C. C. Bailey, M. Alpert, C. Rader, H. Choe, M. Farzan

bioRxiv · Jun 29, 2020Microbiology