Author

N. Skamangas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Pan· 2 shared M. Farzan· 2 shared N. Bronkema· 2 shared T. Ou· 2 shared W. He· 2 shared X. Liu· 2 shared X. Zhang· 2 shared Y. Yin· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBioengineering

A. Pan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4

A. Pan, C. C. Bailey, T. Ou, J. Xu, X. Liu, B. Hu, G. Crynen, N. Skamangas, N. Bronkema, M. Tran, H. Mu, X. Zhang, Y. Yin, M. D. Alpert, W. He, M. Farzan

This study demonstrates that non-antibody protein biologics can undergo affinity maturation in vivo, leading to improved binding affinity and neutralization potency against HIV-1.

bioRxiv · Feb 3, 2024Bioengineering

Heavy-chain CDR3-engineered B cells facilitate in vivo evaluation of HIV-1 vaccine candidates

W. He, T. Ou, N. Skamangas, C. Bailey, N. Bronkema, Y. Guo, Y. Yin, V. Kobzarenko, X. Zhang, A. Pan, X. Liu, A. Allwardt, D. Mitra, B. Quinlan, R. Sanders, , M. Farzan

The paper evaluates HIV-1 vaccine candidates using HCDR3-engineered B cells, finding that SOSIP-TM mRNA-lipid nanoparticles induce stronger anti-apex responses than multimerized SOSIP proteins.

bioRxiv · Nov 7, 2022 · PreprintImmunology