Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products
C. D. Diaz-Celis, C. Canari-Chumpitaz, R. P. Sosa, J. P. Castillo, M. Zhang, E. Cheng, A. Chen, M. Vien, J. Kim, B. Onoa, C. J. Bustamante
This study uses optical tweezers and FRET to identify DNA segments unwrapped during nucleosome mechanical transitions, revealing distinct low- and high-force unwrapping processes.
bioRxiv · Apr 13, 2022Biophysics