Author

J. P. Castillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. J. Bustamante· 2 shared A. B. Tong· 1 shared A. Calixto· 1 shared A. Chen· 1 shared A. K. Cada· 1 shared A. L. Yokom· 1 shared A. Tong· 1 shared B. Onoa· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

C. J. Bustamante

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Author profile →

4 papers

Recent·Most cited

The assembly of wild natural isolates define neuronal integrity and life history traits of co-inhabiting C. elegans.

S. Urquiza-Zurich, V. A. Garcia-Angulo, P. Burdisso, M. F. Palominos, L. Fernandez-Hubeid, J. P. Castillo, A. Calixto

This paper studies how combinations of wild bacterial isolates affect the physiological and behavioral traits of C. elegans, identifying NAD+ as a neuroprotective metabolite.

bioRxiv · Sep 26, 2022 · PreprintMicrobiology

Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products

C. D. Diaz-Celis, C. Canari-Chumpitaz, R. P. Sosa, J. P. Castillo, M. Zhang, E. Cheng, A. Chen, M. Vien, J. Kim, B. Onoa, C. J. Bustamante

This study uses optical tweezers and FRET to identify DNA segments unwrapped during nucleosome mechanical transitions, revealing distinct low- and high-force unwrapping processes.

bioRxiv · Apr 13, 2022Biophysics

Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1

A. K. Cada, M. Remec Pavlin, J. P. Castillo, A. B. Tong, K. P. Larsen, X. Ren, A. L. Yokom, F.-C. Tsai, J. Shiah, P. Bassereau, C. J. Bustamante, J. H. Hurley

This study shows that CHMP1B and IST1 can sever membranes through a friction-driven mechanism, requiring constriction and extensional force, but not VPS4 or spastin.

bioRxiv · Feb 3, 2022 · PreprintBiophysics

A DNA translocase operates by cycling between planarand lock-washer structures

J. P. Castillo, A. Tong, S. Tafoya, P. J. Jardine, C. Bustamante

The paper studies a DNA translocase that adapts its translocation mechanism to different substrates by altering its structural conformation.

bioRxiv · May 22, 2020 · PreprintBiophysics